5 Differences Between Modafinil and Amphetamine

Modafinil vs Amphetamine

Modafinil and Amphetamine may seem to be similar drugs because of their function to stimulate neurological activities. However, their discrete structure and mechanism of action unveil significant differences between the two compounds. It can be understood by the facts given in the support of potential and indications of the drugs.

Modafinil is a different drug from Amphetamine in the following ways:-

Associated Health Conditions
Amphetamine drugs were used in the past for the treatment of stress, depression, and low concentration. Nowadays, this chemical compound is used in the medicines available for treating attention-deficit hyperactivity disorder (ADHD). Amphetamine can also be used as a supplement for treating exogenous obesity. Modafinil, on the other hand, is commonly known as a wakefulness-promoting agent. It is primarily used for palliating the complications of narcolepsy and obstructive sleep apnea. The key function of Modafinil tablets is associated with psychoactivation and euphoria. It activates glutamatergic circuits and helps retain wakefulness for an extended duration.

Dosage
The recommended dosage of Modafinil is a tablet of 200 mg once a day for the treatment of narcolepsy and hypopnea syndrome. One can buy Modafinil online from reliable sources and use it as per the physician’s recommendation for immediate relief. However, this medicine is barely found with any kind of addictive properties.

The dosage of Amphetamine varies from 5 mg to 10 mg, depending on the age and health of the patient. It is strongly recommended to avoid the overdose of Amphetamine as it can cause addiction and severe health complications.

Withdrawal Route
Most of the drugs are excreted from the kidney by glomerular filtration. Amphetamine leaves the body through renal elimination, which often leads to withdrawal symptoms. These symptoms may include depressed mood, lethargy, change in appetite, and anxiety.

As far as Modafinil is concerned, approx 90% of the drug is eliminated through metabolism, primarily by the liver. A study also suggested that individuals using Modafinil tablets did not experience any withdrawal symptoms.

Side-effects
Modafinil tablets promote wakefulness and help retain activeness for long. It has mild side-effects, which may include a severe headache and vomiting sensations.

On the other hand, Amphetamine medicines may have chronic side-effects on the body. It may include hypertension, abdominal pain, obsessive behaviours, and extreme anxiety. Recreational use of this drug can increase the risk of severe heart-related diseases.

Interactions
The interaction of Modafinil with opioids can affect plasma concentrations. If not controlled, withdrawal symptoms may occur.

Amphetamine can interact with a number of drugs and cause severe health conditions. This drug can reduce the effects of sedatives and antipsychotics. In addition to this, taking acidic substances with amphetamine can affect its absorption and increase urinary excretion.

Modafinil tablets have quite distinct properties as compared to amphetamine drugs, including a separate mechanism of action. Anyone suffering from excessive daytime sleepiness and fatigue can get Modafinil online to regain mental energy, improve neurological functions, and procure an active mind.

Source- https://www.drugbank.ca/drugs/DB00182

https://www.pharmaceutical-journal.com/modafinil-lacks-withdrawal-symptoms-researchers-say/20000995.article?firstPass=false

https://www.drugs.com/answers/modafinil-adderall-difference-3125139.html

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